Deprecated: mysql_connect(): The mysql extension is deprecated and will be removed in the future: use mysqli or PDO instead in /home/a26f9f83/public_html/articles/includes/config.php on line 159
The Facts About Glutathione and Parkinsons Disease > NetSparsh - Viral Content you Love & Share

The Facts About Glutathione and Parkinsons Disease

Parkinson's Disease (PD), a devastating illness, occurs in one of every 100 people over 65.

It is a slowly progressing disease of the nervous system that results in progressive destruction of brain cells (neurons) in an area of the brain called the substantia nigra. Death occurs usually as a result of secondary complications such as infection.

One of the mechanisms known to destroy neurons is damage by free radicals or reactive oxygen species - destructive molecules produced by oxidation of the neurotransmitter dopamine.

The Role of Dopamine

The cells of the substantia nigra use dopamine - a chemical messenger between brain or nerve cells - to communicate with cells in another region of the brain called the striatum.

When nigral cells are lost, nigral dopamine levels fall, resulting in a decrease in striatal dopamine.

The typical symptoms of PD - motor function deficiencies characterized by muscle rigidity, jerky movements, rhythmic resting tremors - are the result of low levels of striatal dopamine.

Most dopaminergic drugs used to treat PD, are aimed at temporarily replenishing or mimicking dopamine. They improve some symptoms, but do not restore normal brain function nor halt brain cell destruction.

Dopaminergic drugs are generally effective at first in reducing many PD symptoms, but over time they lose their effect.

They also cause severe side effects because they overstimulate nerve cells elsewhere in the body and cause confusion, hallucinations, nausea and fluctuations in the movement of limbs.

The Role of Antioxidants

When dopaminergic neurons are lost in the course of Parkinson's disease, the metabolism of dopamine is increased - which in turn increases the formation of highly neurotoxic hydroxyl radicals.

The most important free radical scavenger in the cells of the substantia nigra is the powerful brain antioxidant, glutathione. Glutathione levels in PD patients are low.

And as we age, levels of glutathione in the dopaminergic neurons of the substantia nigra decreases. This appears to hasten cell death and advance the progression of PD.

At least 80 percent of the substantia nigra cells are lost before symptoms of Parkinson's disease become apparent. This is why it becomes essential to protect or maintain these cells under oxidative stress.

How does Glutathione help in Parkinson's Disease?

Several factors explain why glutathione is so beneficial in Parkinson's disease.

1. Glutathione increases the sensitivity of the brain to dopamine. So although glutathione doesn't raise dopamine levels, it allows the dopamine in the brain to be more effective.

2. Glutathione's powerful antioxidant activity protects the brain from free radical damage.

3. An even more intriguing benefit of glutathione lies in its powerful detoxification ability.

Its a well known fact that most Parkinson's patients are deficient in their ability to detoxify chemicals to which they are exposed.

The unfortunate few who harbor an inherited flaw in their detoxification pathways are at far greater risk to the brain damaging effects of a wide variety of toxins.

Glutathione is one of the most important components of the liver's detoxification system. Glutathione therapy is one of the most effective techniques for enhancing liver and brain detoxification.

Glutathione treatments considerably improve some of the symptoms of Parkinson's disease including difficulties with rigidity, walking, movement, coordination and speech. A marked reduction of tremor has been observed as well as a decrease in depression.

Glutathione and N-acetyl-L-cysteine (a glutathione precursor) have been shown to be very effective in protecting the nerves in the substantia nigra from being destroyed by oxidative stress.

Glutathione Therapy in Parkinson's Disease

The practical problem in increasing glutathione levels is that taking glutathione itself as a supplement does not boost cellular glutathione levels, since glutathione breaks down in the digestive tract before it reaches the cells.

However, intravenous glutathione therapy and taking glutathione precursors are both effective in boosting intracellular levels of glutathione.

Intravenous Glutathione Therapy:

Intravenous glutathione injections have been shown to have amazing and quick results.

Dr. David Perlmutter, a pioneer in this therapy, has developed a protocol utilized at the Perlmutter Health Center for administering intravenous glutathione to Parkinson's patients.

Following even a single dosage of intravenous glutathione - often in as little as 15 minutes - the ability to walk, turn around and move their arms is almost completely restored.

Glutathione Precursors:

Dietary antioxidants and supplements that increase cellular glutathione, such as alpha lipoic acid, NAC, pycnogenol, the herb silymarin (milk thistle), are effective in restoring normal function.

N-acetyl-cysteine (NAC) and un-denatured, whey protein both supply glutathione precursors intracellularly, enhance the body's production of glutathione and aid the detoxification process.

Other nutritional supplements which aid the detoxification process include selenium, vitamins E and C.

Read the detailed report with references on Parkinson's Disease and Glutathione

Copyright © 2004 Priya Shah

_____________________________________________

About the author: Priya Shah is the Editor of The Glutathione Report, a newsletter featuring regular updates on the health benefits of glutathione. Get a Free report on Glutathione in Health and Disease

____________________________________________

In The News:

This RSS feed URL is deprecated, please update. New URLs can be found in the footers at https://news.google.com/news

Why Nio Is A Valid Alternative To Tesla
Seeking Alpha
Nio is a pure EV automaker, just like Tesla. Nio follows the Tesla strategy in many places. Where there are differences, Nio seems to have a more favorable positioning and strategy. This leads to likely lower capital intensity for Nio, as well as ...


Deseret News

Photos: Funeral directors' expo showcases alternative burial methods
Deseret News
SALT LAKE CITY — As people feel like they don't fit the mold for traditional funeral and burial services, they are opting for alternatives they find more meaningful — some even turning their remains into diamonds, trees or coral reefs. "It's the last ...


CoinDesk

Huobi's US Exchange Sees 30% Boost in Trading for Tether Alternative
CoinDesk
A U.S. cryptocurrency exchange is reporting a significant increase in trades between tether (USDT), the controversial stablecoin that lost its dollar peg this week, and a newer alternative called TrueUSD. At HBUS, the U.S. affiliate of the Singapore ...

and more »

KGUN

Stonegarden Alternative Plan: BOS kept in the dark
KGUN
TUCSON, Ariz. - The Pima County Sheriff is launching an alternative plan to the controversial border security grant -- known as Operation Stonegarden. KGUN9 has learned the command staff discussed keeping the Board of Supervisors in the dark about the ...


Phys.Org

Study supports Standard Model of particle physics, excludes alternative models
Phys.Org
Attempting to "fix" the Standard Model, many alternative models predict that an electron's seemingly uniform sphere is actually asymmetrically squished. One such model, called the Supersymmetric Model, posits that unknown, heavy subatomic particles ...

and more »

City and state fire officials warn about use of alternative heating
Washington Times Herald
While many people will rely on their furnace to keep the home warm, some will rely on alternative heating sources like fireplaces, wood burning stoves and space heaters. Officials say that while those alternative sources can make a home toasty, they ...


Concord Monitor

Michael S. Lewis: Answering alternative facts on child protection
Concord Monitor
This is a disturbing time for the truth. Some powerful voices in New Hampshire are so bound up in defending their political turf and avoiding responsibility for how they have contributed to danger children face in New Hampshire that they are willing to ...


Franklin man in alternative prison program arrested again
New Jersey Herald
FRANKLIN -- A borough man who was participating in a parole program in lieu of prison time for prior drug charges was arrested again Wednesday and charged with distributing heroin near the Franklin Elementary School. Mark Forlenza, 48, formerly of ...


Alternative Nation (blog)

Nirvana Reveal If New Music & Reunion Tour Could Happen
Alternative Nation (blog)
Nirvana members Dave Grohl and Krist Novoselic were interviewed in Kerrang's new 'Nirvana Reunited' magazine. While the magazine suggests the band are back based on their recent Cal Jam reunion performance, Grohl and Novoselic seemed open to ...

and more »
Google News

Treating Arthritis - Naturally

There are actually three common types of arthritis. These are... Read More

Breathing Your Way To Health

Breathing, yes of course we do it, if not we'd... Read More

Your Home is a Toxic Waste Dump!

Did you know that the household and beauty products that... Read More

Portrait of a Medical Intuitive

I am a Medical Intuitive in the San Francisco Bay... Read More

Sun Chlorella and the Benefit

Sun Chlorella is referred to as the Green Magician due... Read More

All Natural Shampoo - 5 Tips

All Natural Shampoo - 5 Tips Here are 5 tips... Read More

Classical Music Therapy

Music, more than entertainment, has played an instrumental role in... Read More

Constipation: A Serious Health Concern

How often do you go to the bathroom and have... Read More

Aloe Vera - No Wonder They Call It The Miracle Plant

Aloe Vera is a member of the Lily family. It... Read More

Dopamine Relieves Pain ? Try Encouraging Your Subconscious To Supply It

Dopamine has long been known to be linked to positive... Read More

Organic Bedding and Organic Mattresses by Prescription Only?

Effective January 1, 2005, California law requires all mattresses contain... Read More

Seven Sinus Headache Solutions

1. Try steam inhalation as one of your sinus headache... Read More

Precious Gems of Wisdom

The New Age should also be called The Stone Age,... Read More

Air Purifiers And Air Filters Can Help The Health Of Allergy And Asthma Sufferers

Indoor air pollution in the form of dander, dust and... Read More

Is Heat or Ice Better for Arthritis Pain?

You probably know that applying heat or ice to a... Read More

Aromatherapy ? Part II: Mind and Emotions

The Sense of Smell forms the greater part of our... Read More

Using Essential Fatty Acids for Reducing Arthritis Joint Pain

Essential fatty acids provide protection for the whole body. In... Read More

Benefits of Alternative Medicine

With the growing number of people being affected by newly... Read More

How to Use Herbal Salves & Ointments to Shrink Your Hemorrhoids

Comfrey Herbal SalveHere is an herbal combination that contains herbs... Read More

What is Hypnosis?

Before anyone experiences hypnosis and starts using it to make... Read More

Aloe Vera - The Medicine And Beauty Treatment Of Choice For Millenniums

I can remember as a young boy that my grandmother... Read More

Aphrodisiacs: Increasing Sexual Desire and Capacity

Are you among the millions of people worldwide who are... Read More

Traditional Chinese Medicine

Traditional Chinese Medicine, over 2000 years old, is an ancient... Read More

Snoring: A Common Sleep Disorder

Sleep consumes as much as one-third or more of the... Read More

Why Air Purifiers Are Not Always The Answer To Indoor Air Quality Problems

Air purifier filters are not always the answer to air... Read More